Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.58 |
| ▸ | HTR1B | P28222 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414181 | 1.00 | HTR1A (0.58) | HTR1AHTR1BSLC6A4 | |
| SCHEMBL10413236 | 1.00 | HTR1A (0.58) | HTR1AHTR1BSLC6A4 | |
| SCHEMBL10413248 | 1.00 | HTR1A (0.58) | HTR1AHTR1BSLC6A4 | |
| SCHEMBL10413276 | 1.00 | HTR1A (0.58) | HTR1AHTR1BSLC6A4 | |
| SCHEMBL10413220 | 1.00 | HTR1A (0.58) | HTR1AHTR1BSLC6A4 | |
| SCHEMBL10413625 | 0.99 | HTR1A (0.56) | HTR1AHTR1BSLC6A4 | |
| SCHEMBL10412989 | 0.97 | HTR1A (0.53) | HTR1AHTR1BSLC6A4 | |
| SCHEMBL10413241 | 0.95 | HTR1A (0.51) | HTR1AHTR1BSLC6A4 | |
| SCHEMBL10414111 | 0.91 | HTR1A (0.54) | HTR1AHTR1BSLC6A4 | |
| SCHEMBL10413753 | 0.88 | HTR1A (0.51) | HTR1AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916143-A | Hydroxyindole esters | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | disclosed |