SCHEMBL104130

SCHEMBL104130

c1ccc(-c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK13 O15264 11/20 0.82
MAPK12 P53778 11/20 0.82
MAPK11 Q15759 11/20 0.82
MAPK14 Q16539 11/20 0.82
RAF1 P04049 5/20 0.82
MAPK9 P45984 1/20 0.82
GCGR P47871 6/20 0.79
NOX1 Q9Y5S8 1/20 0.72
TP53 P04637 1/20 0.68
MAPT P10636 1/20 0.68
BRAF P15056 1/20 0.68
ALOX5 P09917 1/20 0.68
KDM4E B2RXH2 1/20 0.66
ALDH1A1 P00352 1/20 0.66
GLA P06280 1/20 0.66
GAA P10253 1/20 0.66
HPGD P15428 1/20 0.66
KMT2A Q03164 1/20 0.66
MGAM O43451 1/20 0.66
PTPN1 P18031 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28852698 1.00 MAPK13 (0.82) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL27850480 0.98 MAPK13 (0.79) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL5074753 0.98 MAPK13 (0.83) MAPK13MAPK12MAPK11MAPK14RAF1
Methane SCHEMBL3278320 0.98 MAPK13 (0.79) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL16667652 0.96 MAPK13 (0.83) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL739928 0.93 MAPK13 (0.72) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL7228717 0.91 MAPK13 (1.00) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL2949385 0.91 MAPK13 (1.00) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL14514175 0.90 PTPN1 (0.73) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL3456136 0.89 MAPK13 (0.74) MAPK13MAPK12MAPK11MAPK14RAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8118 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260000766-A1 ULTRASOUND OPTOGENETIC COMPOSITIONS AND METHODS UNIV TEXAS (US) 2026-01-01 US claimed
US-12498366-B2 Measurement method for fibroblast growth factor-23 by forming immunocomplexes CANON MEDICAL DIAGNOSTICS CORPORATION (JP) 2025-12-16 US claimed
WO-2025224106-A1 USE OF A COMPOSITION OR THERMOSETTING RESIN OR THERMOSET POLYMER MADE THEREFROM AS BUILD-UP FILM MATERIAL IN A PRINTED CIRCUIT ELEMENT BASF SE (DE) 2025-10-30 WO claimed
EP-4321541-B1 RESIN COMPOSITION, RESIN SHEET, MULTILAYER PRINTED WIRING BOARD AND SEMICONDUCTOR DEVICE MITSUBISHI GAS CHEMICAL CO (JP) 2025-08-06 EP claimed
US-12379379-B2 Assay NEOGEN FOOD SAFETY US HOLDCO CORPORATION (US) 2025-08-05 US claimed
WO-2025122626-A1 HYDROGEN-BONDED FRAMEWORKS NANOPARTICLES FOR SONO-OPTOGENETIC TREATMENT OF BRAIN DISEASES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-06-12 WO claimed
CN-120041039-A Flame-retardant corrosion-resistant coating and preparation method thereof 华瑞(江苏)燃机服务有限公司 2025-05-27 CN claimed
CN-119979129-A Cooling liquid, preparation method thereof, battery and power utilization device 宁德时代新能源科技股份有限公司 2025-05-13 CN claimed
US-20250147425-A1 STRIPPER COMPOSITION AND METHOD FOR FORMING PATTERN USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2025-05-08 US claimed
CN-119937261-A Release agent composition and method of forming pattern using the same 三星显示有限公司 2025-05-06 CN claimed
EP-0019219-A1 Improved photoimaging systems with cyclic hydrazides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-11-26 EP claimed
US-4201590-A Heat sensitive reactive products of hexaarylbiimidazole and antihalation dyes EASTMAN KODAK COMPANY (US) 1980-05-06 US claimed
US-4196002-A HEXAARYLBISMIIDAZOLE, COLORLESS EASTMAN KODAK COMPANY (US) 1980-04-01 US claimed
EP-0005274-A1 Photopolymerisable compositions comprising derivatives of aryl ketones and p-dialkylaminoarylaldehydes as sensitisers for visible light E.I. DU PONT DE NEMOURS AND COMPANY (US) 1979-11-14 EP claimed
US-4162162-A Derivatives of aryl ketones and p-dialkyl-aminoarylaldehydes as visible sensitizers of photopolymerizable compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-07-24 US claimed
US-4082767-A CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-04-04 US claimed
US-4076530-A Dry photographic copying method for producing Te images FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US claimed
US-3997552-A HERBICIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-12-14 US claimed
US-3962029-A CHEMILUMINESCENCE MO OCH DOMSJO AB (SW) 1976-06-08 US claimed
US-3933488-A CHEMILUMINESCENCE FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US claimed