SCHEMBL2949385

SCHEMBL2949385

c1ccc(-c2nc(-c3ccncc3)[nH]c2-c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPK13 O15264 17/20 1.00
MAPK12 P53778 17/20 1.00
MAPK11 Q15759 17/20 1.00
MAPK14 Q16539 17/20 1.00
RAF1 P04049 12/20 1.00
MAPK9 P45984 1/20 1.00
GCGR P47871 4/20 0.82
BRAF P15056 3/20 0.82
ALOX5 P09917 1/20 0.82
BRDT Q58F21 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7228717 1.00 MAPK13 (1.00) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL20710613 0.93 MAPK13 (0.86) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL5921859 0.91 MAPK13 (1.00) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL2650068 0.91 MAPK13 (1.00) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL28486758 0.91 MAPK14 (1.00) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL6469877 0.91 MAPK14 (1.00) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL4552316 0.91 MAPK14 (1.00) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL6469543 0.91 MAPK13 (1.00) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL6469111 0.91 MAPK13 (1.00) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL9195042 0.91 MAPK14 (1.00) MAPK13MAPK12MAPK11MAPK14RAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111057043-A Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method 深圳市贝加电子材料有限公司 2020-04-24 CN claimed
EP-1886759-B1 WATER-SOLUBLE PREFLUX AND USE THEREOF SHIKOKU CHEM (JP) 2016-10-05 EP disclosed
US-7754105-B2 Water-soluble preflux and usage of the same SHIKOKU CHEMICALS CORPORATION (JP) 2010-07-13 US disclosed
US-20080318070-A1 Water-Soluble Preflux and Usage of the Same SHIKOKU CHEMICALS CORPORATION (JP) 2008-12-25 US disclosed
EP-1886759-A1 WATER-SOLUBLE PREFLUX AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2008-02-13 EP disclosed