Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28765157 | 0.84 | NPC1 (0.49) | CYP11B1CYP11B2NPC1RAB9AHDAC3 | |
| SCHEMBL2824553 | 0.83 | MAPT (0.57) | MAPTGAACYP11B1CYP11B2HDAC3 | |
| SCHEMBL10918711 | 0.83 | CYP11B1 (0.51) | CYP11B1CYP11B2NPC1RAB9ATLR7 | |
| SCHEMBL19857760 | 0.82 | CCR9 (0.49) | MAPTCYP11B1CYP11B2NPC1RAB9A | |
| SCHEMBL9244900 | 0.82 | MAPT (0.69) | MAPTGAACA1CA2CA9 | |
| SCHEMBL9252016 | 0.82 | MAPT (0.69) | MAPTGAACA1CA2CA9 | |
| SCHEMBL11061399 | 0.81 | KMT2A (0.65) | MAPTCYP11B1CYP11B2NPC1RAB9A | |
| SCHEMBL11070724 | 0.81 | CYP11B1 (0.50) | GAACYP11B1CYP11B2NPC1RAB9A | |
| SCHEMBL8374908 | 0.81 | MAPT (0.87) | MAPTGAACA1CA2CA9 | |
| SCHEMBL2843778 | 0.81 | BRAF (0.47) | MAPTCYP11B1CYP11B2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4965275-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |
| EP-0330927-A2 | Pyridine-4-carboxylic-acid anilide | BAYER AG (DE) | 1989-09-06 | — | — | EP | disclosed |