Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.52 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413538 | 0.92 | L3MBTL1 (0.57) | L3MBTL1TDP1PTGS1MAPTNR1I2 | |
| SCHEMBL10413073 | 0.87 | L3MBTL1 (0.65) | L3MBTL1TDP1PTGS1MAPTNR1I2 | |
| SCHEMBL11220098 | 0.86 | PTGS1 (0.62) | L3MBTL1TDP1PTGS1MAPTNR1I2 | |
| SCHEMBL11226154 | 0.85 | TDP1 (0.71) | L3MBTL1TDP1PTGS1MAPTNR1I2 | |
| SCHEMBL10414904 | 0.85 | PTGS1 (0.51) | L3MBTL1TDP1PTGS1MAPTNR1I2 | |
| SCHEMBL11416752 | 0.82 | L3MBTL1 (0.53) | L3MBTL1TDP1PTGS1MAPTNR1I2 | |
| SCHEMBL11222454 | 0.82 | L3MBTL1 (0.53) | L3MBTL1TDP1PTGS1MAPTNR1I2 | |
| SCHEMBL10413540 | 0.80 | NR1I2 (0.74) | L3MBTL1TDP1PTGS1MAPTNR1I2 | |
| SCHEMBL10413541 | 0.80 | NR1I2 (0.74) | L3MBTL1TDP1PTGS1MAPTNR1I2 | |
| SCHEMBL11260139 | 0.80 | NR1I2 (0.74) | L3MBTL1TDP1PTGS1MAPTNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963542-A | Cephalosporin derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| US-4264595-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-04-28 | — | — | US | disclosed |