Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414809 | 0.92 | MEN1 (0.35) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10414306 | 0.90 | MAPT (0.33) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10414811 | 0.88 | MAPT (0.31) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10751019 | 0.84 | MEN1 (0.41) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10755934 | 0.84 | MEN1 (0.41) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10756630 | 0.84 | MEN1 (0.41) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10838601 | 0.83 | MEN1 (0.44) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10616980 | 0.83 | MEN1 (0.40) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10839195 | 0.83 | MEN1 (0.42) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10413884 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912214-A | Containing azelidin-2-one ring | HOFFMAN-LA ROCHE INC. (US) | 1990-03-27 | — | — | US | disclosed |