Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413404 | 0.92 | MAPT (0.39) | MEN1KMT2ACCKBRLMNAMAPT | |
| SCHEMBL10413884 | 0.91 | — | — | |
| SCHEMBL10548032 | 0.89 | KLK7 (0.35) | MEN1KMT2ACCKBRLMNAMAPT | |
| SCHEMBL10414306 | 0.82 | MAPT (0.33) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10414811 | 0.81 | MAPT (0.31) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10548753 | 0.80 | LMNA (0.32) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL10414814 | 0.79 | CYP3A4 (0.31) | KMT2AMAPTHSD17B10TDP1 | |
| SCHEMBL10414813 | 0.79 | CYP3A4 (0.31) | KMT2AMAPTHSD17B10TDP1 | |
| SCHEMBL10412836 | 0.79 | NR1I2 (0.32) | KMT2AMAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10412840 | 0.78 | HSD17B10 (0.40) | MEN1KMT2ALMNAMAPTSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912214-A | Containing azelidin-2-one ring | HOFFMAN-LA ROCHE INC. (US) | 1990-03-27 | — | — | US | disclosed |