Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 17/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076096 | 0.92 | ALKBH5 (0.45) | ALKBH5KDM4ENSD2ALDH1A1POLB | |
| SCHEMBL693607 | 0.86 | ALKBH5 (0.48) | ALKBH5CTSA | |
| SCHEMBL11228689 | 0.85 | ALKBH5 (0.52) | ALKBH5ALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL7830050 | 0.85 | ALKBH5 (0.45) | ALKBH5KDM4ENSD2ALDH1A1POLB | |
| SCHEMBL10412743 | 0.82 | ALKBH5 (0.50) | ALKBH5KDM4EALDH1A1POLBMAPT | |
| SCHEMBL11139711 | 0.79 | KDM4E (0.40) | ALKBH5KDM4ENSD2ALDH1A1POLB | |
| SCHEMBL1939982 | 0.78 | ALKBH5 (0.46) | ALKBH5KDM4EALDH1A1CTSA | |
| SCHEMBL10390925 | 0.78 | ALKBH5 (0.43) | ALKBH5KDM4EALDH1A1TDP1CTSA | |
| SCHEMBL8751526 | 0.77 | ALKBH5 (0.56) | ALKBH5KDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL9558930 | 0.76 | ALKBH5 (0.51) | ALKBH5CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906738-A | Water-soluble phenyl- or naphthyl-azo-carboxypyrazolone compounds, containing a fiber-reactive group with a chloratriazinyl moiety and a group of the vinylsulfone series in the pyrazolone coupling component, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-06 | — | — | US | disclosed |