SCHEMBL10413664

SCHEMBL10413664

CSC(=O)CC(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12582310 0.83
SCHEMBL9065118 0.77 FAAH (0.38)
SCHEMBL6511030 0.75
SCHEMBL12452327 0.73
SCHEMBL14996653 0.73
SCHEMBL10389469 0.71 MGAM (0.56)
SCHEMBL2128645 0.71 MGAM (0.56)
SCHEMBL1608 0.71
SCHEMBL15345208 0.71
SCHEMBL24064836 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11781120-B2 Biosynthesis of polyketides Gonzalez, Ramon (US) 2023-10-10 US disclosed
US-11186834-B2 Biosynthesis of products from 1-carbon compounds MOJIA BIOTECH PTE. LTD. (SG) 2021-11-30 US disclosed
US-20210054427-A1 BIOSYNTHESIS OF POLYKETIDES GONZALEZ, RAMON 2021-02-25 US disclosed
US-10822317-B2 Methods and compositions for wound healing QBiotics Pty Ltd (AU) 2020-11-03 US disclosed
US-10793884-B2 Methods and materials for making simvastatin and related compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-10-06 US disclosed
US-10689628-B2 Method of making variant LovD polypeptides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-06-23 US disclosed
US-20190169580-A1 VARIANT LovD POLYPEPTIDE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-06-06 US disclosed
US-20190161462-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING QBIOTICS LIMITED (AU) 2019-05-30 US disclosed
US-20190100741-A1 BIOSYNTHESIS OF PRODUCTS FROM 1-CARBON COMPOUNDS MOJIA BIOTECH PTE. LTD. (SG) 2019-04-04 US disclosed
US-10246689-B2 Variant LovD polypeptide THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-04-02 US disclosed
US-9694090-B2 Process for preparing hyperpolarized substrates and method for MRI BRACCO IMAGING S.P.A. (IT) 2017-07-04 US disclosed
US-20170144981-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING QBIOTICS LIMITED (AU) 2017-05-25 US disclosed
US-20170144981-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING QBIOTICS LIMITED (AU) 2017-05-25 US disclosed
US-20170029790-A1 VARIANT LovD POLYPEPTIDE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-02-02 US disclosed
US-20160068499-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING QBiotics Pty Ltd (AU) 2016-03-10 US disclosed
US-20160068499-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING QBiotics Pty Ltd (AU) 2016-03-10 US disclosed
EP-2940141-A1 Method for the enzymatic production of 3-hydroxy-3-methylbutyric acid from acetone and acetyl-CoA Scientist of Fortune S.A. (LU) 2015-11-04 EP disclosed
US-7413607-B2 Templated semiconductor particles and methods of making 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-08-19 US disclosed
US-4933482-A HYDROGENATION OF BETA-KETO ACID IN PRESENCE OF RUTHENIUM PHOSPHINE COMPLEX TAKASAGO INTERNATIONAL CORPORATION (JP) 1990-06-12 US disclosed
US-4614819-A REACTING A THIOL ESTER COMPOUND WITH 7-AMINOCEPHALOSPORIN IN PRESENCE OF BORON TRIFLUORIDE TOYAMA CHEMICAL CO., LTD. (JP) 1986-09-30 US disclosed