Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | AGER | Q15109 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414536 | 1.00 | FGF23 (0.56) | FGF23ALDH1A1SMN1; SMN2GAATP53 | |
| SCHEMBL1905601 | 0.87 | KDM4E (0.52) | ALDH1A1SMN1; SMN2KDM4ETDP1MAPT | |
| SCHEMBL1905604 | 0.87 | KDM4E (0.52) | ALDH1A1SMN1; SMN2KDM4ETDP1MAPT | |
| SCHEMBL6386356 | 0.85 | NAPRT (0.51) | ALDH1A1SMN1; SMN2GAATP53KDM4E | |
| SCHEMBL6386359 | 0.85 | NAPRT (0.51) | ALDH1A1SMN1; SMN2GAATP53KDM4E | |
| SCHEMBL6806101 | 0.84 | KDM4E (0.49) | FGF23ALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL6806097 | 0.84 | KDM4E (0.49) | FGF23ALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL4061680 | 0.84 | NPC1 (0.54) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL7502908 | 0.84 | PTGS1 (0.44) | ALDH1A1SMN1; SMN2GAAKDM4ETDP1 | |
| SCHEMBL4061684 | 0.84 | NPC1 (0.54) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948796-A | TREATING CEREBO-VASCULARE DISEASES | TOYAMA CHEMICAL CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |