Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.49 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011929 | 0.87 | RAB9A (0.57) | RAB9ANPC1PLOD2CYP1A2CYP2C19 | |
| SCHEMBL6011931 | 0.84 | RAB9A (0.75) | RAB9ANPC1PLOD2CYP1A2PLOD3 | |
| SCHEMBL2051943 | 0.84 | RAB9A (0.75) | RAB9ANPC1PLOD2CYP1A2PLOD3 | |
| SCHEMBL30333799 | 0.83 | RAB9A (0.73) | RAB9ANPC1PLOD2CYP1A2PLOD3 | |
| SCHEMBL29017606 | 0.83 | RAB9A (0.73) | RAB9ANPC1PLOD2CYP1A2PLOD3 | |
| SCHEMBL28172864 | 0.83 | RAB9A (0.73) | RAB9ANPC1PLOD2CYP1A2PLOD3 | |
| Hydrochloric Acid SCHEMBL11622188 | 0.83 | RAB9A (0.73) | RAB9ANPC1PLOD2CYP1A2PLOD3 | |
| SCHEMBL29986829 | 0.83 | RAB9A (0.73) | RAB9ANPC1PLOD2CYP1A2PLOD3 | |
| Bromide SCHEMBL28156394 | 0.83 | RAB9A (0.73) | RAB9ANPC1PLOD2CYP1A2PLOD3 | |
| SCHEMBL11633917 | 0.81 | RAB9A (0.66) | RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925857-A | Pyridinyl-1H-pyrazole-1-alkanamides as antiarrhythmic agents | STERLING DRUG INC. (US) | 1990-05-15 | — | — | US | disclosed |