Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367552 | 0.89 | ACACB (0.37) | ACACBPTPN11 | |
| SCHEMBL17200916 | 0.85 | ACACB (0.35) | ACACB | |
| SCHEMBL15618181 | 0.85 | ACACB (0.35) | ACACB | |
| SCHEMBL2367405 | 0.82 | PPIB (0.34) | SMN1; SMN2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL15622015 | 0.82 | CA1 (0.33) | ACACBCA1CA2 | |
| SCHEMBL10414728 | 0.80 | TP53 (0.44) | SMN1; SMN2NPC1TP53RAB9ALMNA | |
| SCHEMBL9360082 | 0.79 | ACACB (0.36) | ACACB | |
| SCHEMBL18674471 | 0.76 | NR1H2 (0.35) | SMN1; SMN2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL6950971 | 0.76 | PSEN1 (0.37) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL10337495 | 0.73 | ACACB (0.36) | SMN1; SMN2TDP1MAPTL3MBTL1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920195-A | Fluorescent lanthanide chelates | KANKARE JOUKO (FI) | 1990-04-24 | — | — | US | disclosed |
| EP-0203047-A1 | Fluorescent lanthanide chelates | Kankare, Jouko (FI) | 1986-11-26 | — | — | EP | disclosed |