Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.42 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367555 | 0.90 | APP (0.36) | SMN1; SMN2TDP1PTPN11 | |
| SCHEMBL10414727 | 0.80 | SMN1; SMN2 (0.43) | TP53NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL5004498 | 0.72 | ALDH1A1 (0.36) | TDP1MAPTL3MBTL1KDM4E | |
| SCHEMBL13379490 | 0.70 | PTPN11 (0.54) | RAB9ASMN1; SMN2LMNAPOLBMEN1 | |
| SCHEMBL22461364 | 0.70 | POLB (0.67) | TP53NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31311111 | 0.69 | MLYCD (0.54) | TP53NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL21235627 | 0.68 | PTPN11 (0.40) | CA12CA1CA2CA9PTPN11 | |
| SCHEMBL10367814 | 0.68 | MTNR1A (0.38) | TDP1MAPTL3MBTL1KDM4E | |
| SCHEMBL5201034 | 0.68 | VSIR (0.38) | MAPTL3MBTL1 | |
| SCHEMBL2213535 | 0.66 | NAMPT (0.65) | TP53NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920195-A | Fluorescent lanthanide chelates | KANKARE JOUKO (FI) | 1990-04-24 | — | — | US | disclosed |
| EP-0203047-A1 | Fluorescent lanthanide chelates | Kankare, Jouko (FI) | 1986-11-26 | — | — | EP | disclosed |