Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305090 | 0.98 | MAPK1 (0.58) | MAPK1TDP1KMT2AMAPTMEN1 | |
| SCHEMBL30802269 | 0.95 | MAPK1 (0.56) | MAPK1TDP1KMT2AMAPTMEN1 | |
| SCHEMBL6304856 | 0.95 | MAPK1 (0.56) | MAPK1TDP1KMT2AMAPTMEN1 | |
| SCHEMBL29150957 | 0.95 | MAPK1 (0.56) | MAPK1TDP1KMT2AMAPTMEN1 | |
| SCHEMBL10415465 | 0.95 | TDP1 (0.56) | MAPK1TDP1KMT2AMAPTMEN1 | |
| SCHEMBL7590043 | 0.85 | SMN1; SMN2 (0.63) | MAPK1MAPTHPGDKDM4ESMN1; SMN2 | |
| Isopropylbenzene SCHEMBL27842066 | 0.83 | USP5 (0.53) | MAPK1TDP1KMT2AMAPTMEN1 | |
| SCHEMBL6832412 | 0.82 | TSHR (0.55) | KMT2ACES1ALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL11070858 | 0.81 | TDP1 (0.61) | MAPK1TDP1KMT2AMAPTMEN1 | |
| SCHEMBL27976676 | 0.81 | ERCC5 (0.60) | MAPK1MAPTSMN1; SMN2ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4913843-A | AIR DRYABLE COATING OF THERMOPARTICULATING COMPOUND AND RESIN CARRIER IN ORGANIC SOLVENT | WESTINGHOUSE ELECTRIC CORP. (US) | 1990-04-03 | — | — | US | disclosed |