SCHEMBL305090

SCHEMBL305090

O=CCC(=O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.58
TDP1 Q9NUW8 3/20 0.58
KMT2A Q03164 3/20 0.58
MAPT P10636 2/20 0.58
MEN1 O00255 2/20 0.58
CYP3A4 P08684 2/20 0.58
HPGD P15428 2/20 0.58
CES1 P23141 2/20 0.58
KDM4E B2RXH2 1/20 0.58
ALOX15 P16050 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
NR4A2 P43354 1/20 0.58
ALDH1A1 P00352 6/20 0.54
GSK3B P49841 2/20 0.54
PTPN1 P18031 2/20 0.54
HIF1A Q16665 2/20 0.54
TRPA1 O75762 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.52
LMNA P02545 1/20 0.52
CYP2C19 P33261 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30802269 0.98 MAPK1 (0.56) MAPK1TDP1KMT2AMAPTMEN1
SCHEMBL29150957 0.98 MAPK1 (0.56) MAPK1TDP1KMT2AMAPTMEN1
SCHEMBL10415465 0.98 TDP1 (0.56) MAPK1TDP1KMT2AMAPTMEN1
SCHEMBL6304856 0.98 MAPK1 (0.56) MAPK1TDP1KMT2AMAPTMEN1
SCHEMBL10414732 0.98 MAPK1 (0.56) MAPK1TDP1KMT2AMAPTMEN1
SCHEMBL7590043 0.87 SMN1; SMN2 (0.63) MAPK1MAPTHPGDKDM4ESMN1; SMN2
Isopropylbenzene SCHEMBL27842066 0.85 USP5 (0.53) MAPK1TDP1KMT2AMAPTMEN1
SCHEMBL6832412 0.84 TSHR (0.55) KMT2ACES1ALOX15SMN1; SMN2ALDH1A1
SCHEMBL11070858 0.83 TDP1 (0.61) MAPK1TDP1KMT2AMAPTMEN1
SCHEMBL27976676 0.82 ERCC5 (0.60) MAPK1MAPTSMN1; SMN2ALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250114282-A1 Dental materials and methods of making and using thereof Huang, Chong (US) 2025-04-10 US claimed
US-20240423878-A2 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-12-26 US claimed
CN-115297953-B Porous membranes comprising adsorbent particles for improved urea capture 德国科技术基金会 2024-10-15 CN claimed
CN-116964139-B Photoinitiator resin with dibenzoylmethane substructure 太阳化学有限公司 2024-07-12 CN claimed
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-07-04 US claimed
US-20240197577-A1 SELF-ADHESIVE DENTAL MATERIAL KULZER GMBH (DE) 2024-06-20 US claimed
EP-4312947-A1 SELF-ADHESIVE FISSURE SEALANT Kulzer GmbH (DE) 2024-02-07 EP claimed
EP-4312945-A1 SELF-ADHESIVE DENTAL MATERIAL Kulzer GmbH (DE) 2024-02-07 EP claimed
CN-116964139-A Photoinitiator resin with dibenzoylmethane substructure 太阳化学公司 2023-10-27 CN claimed
EP-3976878-B1 METHODS OF MAKING A DEFLECTION MEMBER PROCTER & GAMBLE (US) 2023-07-05 EP claimed
WO-2003072793-A2 METHOD FOR PRODUCING ALCOHOLS FROM SUBSTRATES BY USING OXIDE REDUCTASES, TWO-PHASE SYSTEM COMPRISING AN AQUEOUS PHASE AND AN ORGANIC PHASE AND DEVICE FOR CARRYING OUT SAID METHOD Forschungszentrum Jülich GmbH (DE) 2003-09-04 WO claimed
US-6500554-B2 SURFACE TREATMENT OF METAL BY APPLYING FUNCTIONALIZED ALKOXYSILANE; EXTRUDING MELT OF POLYAMIDE MOLDING; DRYING; CORROSION RESISTANCE; PROTECTIVE COATINGS DEGUSSA AG (DE) 2002-12-31 US claimed
US-20010023537-A1 SURFACE TREATMENT OF METAL BY APPLYING FUNCTIONALIZED ALKOXYSILANE; EXTRUDING MELT OF POLYAMIDE MOLDING; DRYING; CORROSION RESISTANCE; PROTECTIVE COATINGS DEGUSSA-HUELS (DE) 2001-09-27 US claimed
US-6288155-B1 CONTAINING DOLOMITE COMPOUND AND ZINC SALT OF AN ORGANIC ACID AJINOMOTO CO., INC. (JP) 2001-09-11 US claimed
EP-0838485-B1 Esterified hydrophilic resins stable to saponification and particularly suited for aqueous systems DEGUSSA (DE) 2000-04-26 EP claimed
US-5962582-A Hydrophilic synthetic resins, esterified for stability to hydrolysis, which are particularly suitable for aqueous systems HUELS AKTIENGESELLSCHAFT (DE) 1999-10-05 US claimed
US-5783621-A Method of decreasing bleed fom organic-based formulations and anti-bleed compositions JOHNSON MATTHEY, INC. (US) 1998-07-21 US claimed
EP-0345553-A2 Photographic recording material Agfa-Gevaert AG (DE) 1989-12-13 EP claimed
EP-0108023-B1 PROCESS FOR THE STABILIZATION OF VINYL CHLORIDE POLYMERS RHONE-POULENC CHIMIE (FR) 1986-12-17 EP claimed
EP-0108023-A1 Process for the stabilization of vinyl chloride polymers RHONE-POULENC CHIMIE (FR) 1984-05-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197577-A1 SELF-ADHESIVE DENTAL MATERIAL CAD, MTHFD2, MAT2B MAPK1 3736/4885TDP1 818/4885KMT2A 2624/4885
US-20240423878-A2 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS MAPK1 3982/4885TDP1 563/4885KMT2A 2837/4885
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS MAPK1 3982/4885TDP1 563/4885KMT2A 2837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.