SCHEMBL10414972

SCHEMBL10414972

CCOC(=O)C(CC)C(=O)C(=O)OBr

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
TRPA1 O75762 1/20 0.35
LMNA P02545 2/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 3/20 0.33
KMT2A Q03164 3/20 0.33
GAA P10253 2/20 0.33
MEN1 O00255 2/20 0.33
ALOX15 P16050 1/20 0.33
MGAM O43451 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SOAT1 P35610 1/20 0.33
HPGD P15428 2/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MMP8 P22894 1/20 0.33
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL717299 0.85 ALDH1A1 (0.40) ALDH1A1TRPA1LMNAHSD17B10TDP1
SCHEMBL6979692 0.81 ALDH1A1 (0.40) ALDH1A1TRPA1LMNAHSD17B10TDP1
SCHEMBL10932012 0.78 SOAT1 (0.52) ALDH1A1LMNAHSD17B10TDP1KMT2A
SCHEMBL230068 0.78 ALDH1A1 (0.50) ALDH1A1TRPA1LMNAHSD17B10TDP1
SCHEMBL3061368 0.77 ALDH1A1 (0.40) ALDH1A1TRPA1LMNAHSD17B10TDP1
SCHEMBL28054134 0.75 ALDH1A1 (0.48) ALDH1A1TRPA1LMNAHSD17B10TDP1
SCHEMBL26658212 0.75 ALDH1A1 (0.48) ALDH1A1TRPA1LMNAHSD17B10TDP1
Ammonia Solution, Strong SCHEMBL27830684 0.75 ALDH1A1 (0.48) ALDH1A1TRPA1LMNAHSD17B10TDP1
SCHEMBL28077349 0.75 ALDH1A1 (0.48) ALDH1A1TRPA1LMNAHSD17B10TDP1
Hydrochloric Acid SCHEMBL27522636 0.75 ALDH1A1 (0.48) ALDH1A1TRPA1LMNAHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4973695-A FROM UNSATURATED ALDEHYDE OR KETONE WITH OXODIESTER SUGAI CHEMICAL IND. CO., LTD. (JP) 1990-11-27 US disclosed