Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042352 | 1.00 | ELANE (0.78) | ELANEMEN1KMT2AHSD17B10MAPT | |
| SCHEMBL1041258 | 1.00 | ELANE (0.78) | ELANEMEN1KMT2AHSD17B10MAPT | |
| SCHEMBL4191624 | 1.00 | ELANE (0.78) | ELANEMEN1KMT2AHSD17B10MAPT | |
| SCHEMBL4566025 | 0.98 | ELANE (0.80) | ELANEMEN1KMT2AHSD17B10MAPT | |
| SCHEMBL272505 | 0.94 | ELANE (0.82) | ELANEMEN1KMT2ATSHR | |
| SCHEMBL6136019 | 0.92 | ELANE (0.73) | ELANEMEN1KMT2A | |
| SCHEMBL693242 | 0.92 | ELANE (0.73) | ELANEMEN1KMT2A | |
| SCHEMBL2572932 | 0.92 | ELANE (0.73) | ELANEMEN1KMT2A | |
| SCHEMBL29633656 | 0.92 | ELANE (0.73) | ELANEMEN1KMT2A | |
| SCHEMBL692829 | 0.91 | ELANE (0.76) | ELANEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903344-B1 | Quinazolin-4-one derivatives, their preparation and their use as hair growth promoters or in external compositions for skin | SHISEIDO CO LTD (JP) | 2011-01-26 | — | — | EP | disclosed |
| US-5972929-A | Quinazolinone derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0903344-A1 | Quinazolin-4-one derivatives, their preparation and their use as hair growth promoters or in external compositions for skin | SHISEIDO COMPANY LIMITED (JP) | 1999-03-24 | — | — | EP | disclosed |