SCHEMBL6136019

SCHEMBL6136019

O=c1oc(CCCCCCCCc2nc3ccccc3c(=O)o2)nc2ccccc12

nearest known ligand 0.73

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ELANE P08246 18/20 0.73
MEN1 O00255 1/20 0.66
KMT2A Q03164 1/20 0.66
C1R P00736 1/20 0.57
PDE10A Q9Y233 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2572932 1.00 ELANE (0.73) ELANEMEN1KMT2AC1RPDE10A
SCHEMBL693242 1.00 ELANE (0.73) ELANEMEN1KMT2AC1RPDE10A
SCHEMBL29633656 1.00 ELANE (0.73) ELANEMEN1KMT2AC1RPDE10A
SCHEMBL29444886 0.98 ELANE (0.76) ELANEMEN1KMT2AC1RPDE10A
SCHEMBL692829 0.98 ELANE (0.76) ELANEMEN1KMT2AC1RPDE10A
SCHEMBL4191624 0.92 ELANE (0.78) ELANEMEN1KMT2A
SCHEMBL1041508 0.92 ELANE (0.78) ELANEMEN1KMT2A
SCHEMBL1042352 0.92 ELANE (0.78) ELANEMEN1KMT2A
SCHEMBL1041258 0.92 ELANE (0.78) ELANEMEN1KMT2A
SCHEMBL692733 0.91 ELANE (0.81) ELANEMEN1KMT2AC1RPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0737231-B2 THERMAL STABILIZED RESIN COMPOSITIONS KOLON INC (KR) 2005-11-02 EP disclosed
EP-0737231-B1 THERMAL STABILIZED RESIN COMPOSITIONS KOLON INC (KR) 2000-03-08 EP disclosed
US-5849820-A Thermal stabilized resin compositions KOLON INDUSTRIES, INC. (KR) 1998-12-15 US disclosed