Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.77 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.77 |
| ▸ | MIF | P14174 | 1/20 | 0.77 |
| ▸ | PDE4A | P27815 | 1/20 | 0.77 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.77 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10416886 | 0.89 | ADORA3 (0.70) | PTGS1ADORA3MIFPDE4APDE4D | |
| SCHEMBL10416885 | 0.89 | ADORA3 (0.70) | PTGS1ADORA3MIFPDE4APDE4D | |
| SCHEMBL10416573 | 0.88 | PTGS1 (0.69) | PTGS1ADORA3MIFPDE4APDE4D | |
| SCHEMBL10416574 | 0.88 | PTGS1 (0.69) | PTGS1ADORA3MIFPDE4APDE4D | |
| SCHEMBL10417305 | 0.88 | PTGS1 (0.85) | PTGS1ADORA3MIFPDE4APDE4D | |
| Iguratimod SCHEMBL26326 | 0.87 | PTGS1 (1.00) | PTGS1ADORA3MIFPDE4APDE4D | |
| Iguratimod SCHEMBL29366981 | 0.87 | PTGS1 (1.00) | PTGS1ADORA3MIFPDE4APDE4D | |
| Iguratimod SCHEMBL5455197 | 0.86 | PTGS1 (0.98) | PTGS1ADORA3MIFPDE4APDE4D | |
| SCHEMBL10416621 | 0.85 | PTGS1 (0.74) | PTGS1ADORA3MIFPDE4APDE4D | |
| SCHEMBL10415484 | 0.85 | PTGS1 (0.74) | PTGS1ADORA3MIFPDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4954518-A | Antiinflammatory agents | TOYAMA CHEMICAL COMPANY, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |