Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9806196 | 0.94 | KMT2A (0.54) | KMT2AMEN1TP53POLBTRPV1 | |
| SCHEMBL9797437 | 0.88 | CYP3A4 (0.50) | TRPV1LMNA | |
| SCHEMBL9797246 | 0.88 | KMT2A (0.49) | KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9797418 | 0.87 | KMT2A (0.48) | KMT2AMEN1 | |
| SCHEMBL9797470 | 0.84 | CYP3A4 (0.54) | KMT2AMEN1TP53POLBTRPV1 | |
| Fumaric Acid SCHEMBL9797372 | 0.81 | TRPV1 (0.47) | POLBTRPV1LMNA | |
| Maleic Acid SCHEMBL9797355 | 0.81 | TRPV1 (0.47) | POLBTRPV1LMNA | |
| SCHEMBL9797314 | 0.80 | KCNH2 (0.48) | TP53POLBLMNA | |
| SCHEMBL9806220 | 0.80 | KMT2A (0.60) | KMT2AMEN1TP53POLBTRPV1 | |
| SCHEMBL9797289 | 0.79 | CYP3A4 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935418-A | Medical compositions of 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines and use thereof | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-06-19 | — | — | US | claimed |
| US-4794181-A | ANTIDEPRESSANTS, ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-12-27 | — | — | US | claimed |