Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10416913 | 0.85 | SLC2A1 (0.57) | SLC2A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| Picumeterol SCHEMBL156907 | 0.85 | SLC2A1 (0.57) | SLC2A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| Picumeterol SCHEMBL83175 | 0.85 | SLC2A1 (0.57) | SLC2A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| Picumeterol SCHEMBL9857897 | 0.85 | SLC2A1 (0.57) | SLC2A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| Picumeterol SCHEMBL29414334 | 0.85 | SLC2A1 (0.57) | SLC2A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2170810 | 0.84 | SLC2A1 (0.44) | SLC2A1HTTSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL10391329 | 0.84 | SLC2A1 (0.57) | SLC2A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| Picumeterol SCHEMBL666136 | 0.82 | SLC2A1 (0.68) | SLC2A1SMN1; SMN2ALDH1A1KDM4ECYP1A2 | |
| Picumeterol SCHEMBL9858096 | 0.82 | SLC2A1 (0.68) | SLC2A1SMN1; SMN2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL10417923 | 0.82 | SLC2A1 (0.43) | SLC2A1KDM4ECYP3A4ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4937251-A | TREATING ASTHMA AND BRONCHITIS; ADRENERGIC STIMULANTS | GLAXO GROUP LIMITED (GB) | 1990-06-26 | — | — | US | disclosed |