Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10417923 | 0.88 | SLC2A1 (0.43) | SLC2A1ADRB2LMNAADRB1HTR1A | |
| Picumeterol SCHEMBL29414334 | 0.88 | SLC2A1 (0.57) | SLC2A1ADRB2ADRB1HTR1ASLC6A2 | |
| Picumeterol SCHEMBL83175 | 0.88 | SLC2A1 (0.57) | SLC2A1ADRB2ADRB1HTR1ASLC6A2 | |
| Picumeterol SCHEMBL9857897 | 0.88 | SLC2A1 (0.57) | SLC2A1ADRB2ADRB1HTR1ASLC6A2 | |
| SCHEMBL10416913 | 0.88 | SLC2A1 (0.57) | SLC2A1ADRB2ADRB1HTR1ASLC6A2 | |
| Picumeterol SCHEMBL156907 | 0.88 | SLC2A1 (0.57) | SLC2A1ADRB2ADRB1HTR1ASLC6A2 | |
| SCHEMBL10391329 | 0.87 | SLC2A1 (0.57) | SLC2A1ADRB2ADRB1HTR1ASLC6A2 | |
| SCHEMBL15295668 | 0.86 | SYK (0.37) | SLC2A1SYKHRH1HTTALDH1A1 | |
| Fumaric Acid SCHEMBL9857939 | 0.85 | SLC2A1 (0.59) | SLC2A1HTTALDH1A1PKMRAB9A | |
| SCHEMBL10416510 | 0.84 | SLC2A1 (0.47) | SLC2A1HTTALDH1A1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3199164-A1 | PROCESSES FOR MAKING LACTOSE UTILIZING PRE-CLASSIFICATION TECHNIQUES AND PHARMACEUTICAL FORMULATIONS FORMED THEREFROM | Glaxo Group Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| EP-1848444-B1 | PROCESSES FOR MAKING LACTOSE UTILIZING PRE-CLASSIFICATION TECHNIQUES AND PHARMACEUTICAL FORMULATIONS FORMED THEREFROM | GLAXO GROUP LTD (GB) | 2016-11-09 | — | — | EP | claimed |
| US-9278767-B2 | Direct fill dry powder systems with dosing heads configured for on/off controlled flow | ORIEL THERAPEUTICS, INC. (US) | 2016-03-08 | — | — | US | claimed |
| EP-2346556-B1 | DRY POWDER INHALERS WITH DUAL PIERCING MEMBERS AND RELATED DEVICES AND METHODS | ORIEL THERAPEUTICS INC (US) | 2014-11-05 | — | — | EP | claimed |
| US-8776840-B2 | Tubular dry powder feeders with axially applied vibration for dry powder filling systems | ORIEL THERAPEUTICS, INC. (US) | 2014-07-15 | — | — | US | claimed |
| US-8720497-B2 | Direct fill dry powder systems with dosing heads configured for on/off controlled flow | ORIEL THERAPEUTICS, INC. (US) | 2014-05-13 | — | — | US | claimed |
| US-8671938-B2 | Inhalers with airway disks having discrete airway channels and related disks and methods | ORIEL THERAPEUTICS, INC. (US) | 2014-03-18 | — | — | US | claimed |
| US-20130118490-A1 | INHALERS WITH AIRWAY DISKS HAVING DISCRETE AIRWAY CHANNELS AND RELATED DISKS AND METHODS | ORIEL THERAPEUTICS INC (US) | 2013-05-16 | — | — | US | claimed |
| EP-2536635-A2 | DIRECT FILL DRY POWDER SYSTEMS WITH DOSING HEADS CONFIGURED FOR ON/OFF CONTROLLED FLOW | Oriel Therapeutics, Inc. (US) | 2012-12-26 | — | — | EP | claimed |
| WO-2011106242-A2 | TUBULAR DRY POWDER FEEDERS WITH AXIALLY APPLIED VIBRATION FOR DRY POWDER FILLING SYSTEMS | ORIEL THERAPEUTICS, INC. (US) | 2011-09-01 | — | — | WO | claimed |
| EP-1686960-A4 | INHALABLE PHARMACEUTICAL FORMULATIONS EMPLOYING LACTOSE ANHYDRATE AND METHODS OF ADMINISTERING THE SAME | GLAXO GROUP LTD (GB) | 2007-03-07 | — | — | EP | claimed |
| WO-2006086270-A1 | PROCESSES FOR MAKING LACTOSE UTILIZING PRE-CLASSIFICATION TECHNIQUES AND PHARMACEUTICAL FORMULATIONS FORMED THEREFROM | GLAXO GROUP LIMITED (GB) | 2006-08-17 | — | — | WO | claimed |
| WO-2006086130-A2 | PROCESS FOR CRYSTALLIZING LACTOSE PARTICLES FOR USE IN PHARMACEUTICAL FORMULATIONS | GLAXO GROUP LIMITED (GB) | 2006-08-17 | — | — | WO | claimed |
| EP-1686960-A2 | INHALABLE PHARMACEUTICAL FORMULATIONS EMPLOYING LACTOSE ANHYDRATE AND METHODS OF ADMINISTERING THE SAME | GLAXO GROUP LIMITED (GB) | 2006-08-09 | — | — | EP | claimed |
| EP-1137453-B1 | DRY POWDER INHALER | GLAXO GROUP LTD (GB) | 2006-02-22 | — | — | EP | claimed |
| WO-2005044186-A2 | INHALABLE PHARMACEUTICAL FORMULATIONS EMPLOYING DESICCATING AGENTS AND METHODS OF ADMINISTERING THE SAME | GLAXO GROUP LIMITED (GB) | 2005-05-19 | — | — | WO | claimed |
| WO-2005044187-A2 | INHALABLE PHARMACEUTICAL FORMULATIONS EMPLOYING LACTOSE ANHYDRATE AND METHODS OF ADMINISTERING THE SAME | GLAXO GROUP LIMITED (GB) | 2005-05-19 | — | — | WO | claimed |
| US-6553987-B1 | Dry powder inhaler | SMITHKLINE BEECHAM CORPORATION | 2003-04-29 | — | — | US | claimed |
| EP-1137453-A1 | DRY POWDER INHALER | GLAXO GROUP LIMITED (GB) | 2001-10-04 | — | — | EP | claimed |
| WO-2000035522-A1 | DRY POWDER INHALER | GLAXO GROUP LIMITED (GB) | 2000-06-22 | — | — | WO | claimed |