SCHEMBL10416596

SCHEMBL10416596

C=C(C)C(=O)OCCN(C)C.O=S(=O)(O)C=Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
BCHE P06276 5/20 0.43
ACHE P22303 5/20 0.43
CHRM1 P11229 3/20 0.38
PPARG P37231 2/20 0.37
GAA P10253 1/20 0.37
CHRM2 P08172 2/20 0.37
CHRM4 P08173 2/20 0.37
CHRM5 P08912 2/20 0.37
CHRM3 P20309 2/20 0.37
KDM4E B2RXH2 1/20 0.36
RRM1 P23921 1/20 0.36
AKR1B10 O60218 1/20 0.36
AKR1B1 P15121 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4968472 0.86 PPARG (0.39) ALDH1A1PPARGGAAAKR1B10AKR1B1
SCHEMBL28211115 0.85 PPARG (0.39) ALDH1A1PPARGGAAAKR1B10AKR1B1
SCHEMBL15901615 0.84 TDP1 (0.41) ALDH1A1PPARGGAAKDM4EAKR1B10
Cinnamic Acid SCHEMBL11638446 0.84 BCHE (0.51) ALDH1A1BCHEACHECHRM1AKR1B10
SCHEMBL28322996 0.83 THRB (0.55) ALDH1A1PPARGGAAKDM4EAKR1B10
Vinylsulfonic Acid SCHEMBL28072676 0.82 PPARG (0.37) ALDH1A1PPARGGAAKDM4EAKR1B10
Styrene SCHEMBL446411 0.82 CHRM1 (0.43) ALDH1A1BCHEACHECHRM1CHRM2
SCHEMBL5397617 0.81 BCHE (0.43) ALDH1A1BCHEACHECHRM1CHRM2
Styrene SCHEMBL5397619 0.80 CHRM1 (0.41) ALDH1A1BCHEACHECHRM1CHRM2
SCHEMBL15901721 0.80 HTT (0.38) ALDH1A1PPARGGAAKDM4EAKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4938803-A Nonhydrolyzing NALCO CHEMICAL COMPANY (US) 1990-07-03 US claimed