Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10952940 | 0.84 | PTGS1 (0.60) | GAAAKR1C3AKR1C2PTGS1PTK2 | |
| SCHEMBL7560567 | 0.80 | KDM1A (0.66) | PTK2PTGS2MAPTHSD17B10PIK3CG | |
| Hydrochloric Acid SCHEMBL22716096 | 0.79 | KMT2A (0.67) | PTK2PTGS2MAPTHSD17B10PIK3CG | |
| SCHEMBL27792302 | 0.79 | PTGS1 (0.68) | GAAPTGS1PTK2PTGS2MAPT | |
| SCHEMBL10416623 | 0.79 | PTGS1 (0.52) | GAAPTGS1PTGS2MAPTKEAP1 | |
| SCHEMBL28888760 | 0.77 | PTK2 (0.48) | GAAPTGS1PTK2PTGS2MAPK1 | |
| SCHEMBL10416920 | 0.77 | MAPK1 (0.56) | PTGS1PTK2PTGS2MAPK1MAPT | |
| SCHEMBL11152945 | 0.76 | CA1 (0.56) | GAAAKR1C3AKR1C2PTGS1PTGS2 | |
| SCHEMBL10895905 | 0.75 | AKR1C3 (0.59) | GAAAKR1C3AKR1C2MAPK1MAPT | |
| SCHEMBL10785269 | 0.74 | GAA (0.70) | GAAAKR1C3AKR1C2EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4954518-A | Antiinflammatory agents | TOYAMA CHEMICAL COMPANY, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |