Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 11/20 | 0.36 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10419815 | 0.81 | SMPD1 (0.39) | TLR4CNR2 | |
| SCHEMBL8431664 | 0.81 | TLR4 (0.45) | TLR4LY96 | |
| SCHEMBL10417944 | 0.76 | TLR4 (0.48) | TLR4LY96 | |
| SCHEMBL9511533 | 0.76 | TLR4 (0.48) | TLR4LY96 | |
| SCHEMBL9511906 | 0.75 | TLR4 (0.41) | TLR4LY96 | |
| SCHEMBL8066951 | 0.75 | TLR4 (0.46) | TLR4 | |
| SCHEMBL9748621 | 0.75 | TLR4 (0.46) | TLR4CNR2CNR1 | |
| SCHEMBL6801798 | 0.74 | TLR4 (0.41) | TLR4LY96 | |
| SCHEMBL9515118 | 0.74 | TLR4 (0.44) | TLR4LY96CNR2 | |
| SCHEMBL9515090 | 0.74 | TLR4 (0.44) | TLR4LY96CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925929-A | ANTITUMOR AGENTS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1990-05-15 | — | — | US | disclosed |