Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 14/20 | 0.46 |
| ▸ | CNR2 | P34972 | 6/20 | 0.35 |
| ▸ | CNR1 | P21554 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066951 | 0.84 | TLR4 (0.46) | TLR4 | |
| SCHEMBL6800817 | 0.82 | TLR4 (0.54) | TLR4 | |
| SCHEMBL7510999 | 0.78 | SELP (0.40) | TLR4 | |
| SCHEMBL6800791 | 0.77 | TLR4 (0.41) | TLR4 | |
| SCHEMBL8431613 | 0.76 | TLR4 (0.54) | TLR4 | |
| SCHEMBL10417895 | 0.75 | TLR4 (0.36) | TLR4CNR2CNR1 | |
| SCHEMBL9747848 | 0.73 | TLR4 (0.48) | TLR4CNR2 | |
| SCHEMBL10417935 | 0.73 | TLR4 (0.44) | TLR4CNR2CNR1 | |
| SCHEMBL8521582 | 0.73 | TLR4 (0.55) | TLR4 | |
| Pyridine SCHEMBL7507612 | 0.72 | TLR4 (0.35) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226381-B1 | NOVEL GLUCOPYRANOSE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-02-05 | — | — | EP | claimed |
| EP-0226381-A2 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-06-24 | — | — | EP | claimed |