SCHEMBL104184

SCHEMBL104184

O=Cc1ccc(Br)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29745657 1.00
Water SCHEMBL28840491 0.98 ALDH1A1 (0.41)
Glycine SCHEMBL29043084 0.85 ALDH1A1 (0.37)
SCHEMBL27827254 0.79 CYP11B1 (0.33)
SCHEMBL6273189 0.79 ALDH1A1 (0.45)
SCHEMBL6852107 0.79 ALDH1A1 (0.45)
SCHEMBL171899 0.76
SCHEMBL3210875 0.76
SCHEMBL15067997 0.76
SCHEMBL1356310 0.75 ALDH1A1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2178 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116768937-A Acid-sensitive iridium complex based on isoquinoline benzothiophene and application thereof 南京大学 2023-09-19 CN claimed
WO-2023155777-A1 N- [ (6-BROMOPYRIDIN-3-YL) METHYL] -2-METHOXYETHAN-1-AMINE SALTS AND PREPARATION THEREOF BEIGENE (SUZHOU) CO., LTD. (CN) 2023-08-24 WO claimed
CN-115626890-A Diamine monomer with bulky alkynyl side group and preparation method and application thereof 波米科技有限公司 2023-01-20 CN claimed
CN-115477609-A PD-L1 protein degradation agent based on hydrophobic label technology and application thereof 浙江师范大学 2022-12-16 CN claimed
CN-112479991-A Preparation method of 2-bromo-5-aldehyde pyridine 重庆三圣实业股份有限公司 2021-03-12 CN claimed
CN-107253930-A A kind of preparation method of the aldehyde radical pyridine of 2 bromine 5 上海康鹏科技有限公司 2017-10-17 CN claimed
CN-107056690-A A kind of preparation method of the formaldehyde of 6 bromopyridine 3 上海康鹏科技有限公司 2017-08-18 CN claimed
CN-1740169-B Arylmethylamine derivatives for use as tryptase inhibitors AVENTIS PHARMA INC 2010-04-21 CN claimed
CN-1740169-A Arylmethylamine derivatives for use as tryptase inhibitors AVENTIS PHARMA INC (US) 2006-03-01 CN claimed
EP-4748838-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-27 EP disclosed
US-12637461-B2 Compounds for the activation of AMPK PFIZER INC. (US) 2026-05-26 US disclosed
US-12630527-B2 Broad spectrum anti-cancer compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-19 US disclosed
EP-4739397-A1 FUSED PYRAZOLE DERIVATIVES AS USP1 INHIBITORS Exelixis, Inc. (US) 2026-05-13 EP disclosed
CN-122010826-A Preparation method of high-purity 2-bromo-5-aldehyde pyridine 山东丰金制药有限公司 2026-05-12 CN disclosed
EP-0508393-A1 N-arylheteroarylalkyl imidazol-2-one compounds for treatment of circulatory disorders G.D. Searle & Co. (US) 1992-10-14 EP disclosed
US-5001138-A Insecticides NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) 1991-03-19 US disclosed
US-4845106-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-07-04 US disclosed
US-4742060-A 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) 1988-05-03 US disclosed
EP-0244728-A2 Use of heteroarylethyl amines to stimulate animal growth, heteroarylethyl amines and process for their preparation BAYER AG (DE) 1987-11-11 EP disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 EP disclosed