Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10419983 | 0.83 | ELANE (0.45) | ELANEALDH1A1MAPT | |
| SCHEMBL10418947 | 0.82 | ELANE (0.42) | ELANESMN1; SMN2NPC1TP53 | |
| SCHEMBL10418966 | 0.82 | ELANE (0.42) | ELANEALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL10419558 | 0.82 | ELANE (0.49) | ELANECASP1 | |
| SCHEMBL10418978 | 0.81 | ELANE (0.41) | ELANECASP1 | |
| SCHEMBL10419560 | 0.81 | ELANE (0.43) | ELANEALDH1A1GAA | |
| SCHEMBL10418979 | 0.80 | FAAH (0.42) | ELANECASP1 | |
| SCHEMBL9342290 | 0.80 | ELANE (0.60) | ELANESMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL10711875 | 0.80 | SMN1; SMN2 (0.42) | ELANESMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL10418949 | 0.79 | ELANE (0.40) | ELANESMN1; SMN2RAB9ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4965260-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1990-10-23 | — | — | US | disclosed |