Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 5/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10419353 | 1.00 | TDP1 (0.42) | TDP1HTTMAPTMEN1KMT2A | |
| SCHEMBL24342349 | 0.78 | TDP1 (0.45) | TDP1HTTMAPTMEN1KMT2A | |
| SCHEMBL4378106 | 0.76 | MAPT (0.48) | TDP1HTTMAPTMEN1KMT2A | |
| SCHEMBL4378103 | 0.76 | MAPT (0.48) | TDP1HTTMAPTMEN1KMT2A | |
| SCHEMBL16277300 | 0.74 | HCAR2 (0.35) | DGAT1 | |
| SCHEMBL16277299 | 0.74 | HCAR2 (0.35) | DGAT1 | |
| SCHEMBL7871608 | 0.74 | TSHR (0.41) | TDP1RECQLGAAALDH1A1DGAT1 | |
| SCHEMBL1061841 | 0.71 | CYP2C9 (0.46) | TDP1HTTMAPTMEN1KMT2A | |
| SCHEMBL1061842 | 0.71 | CYP2C9 (0.46) | TDP1HTTMAPTMEN1KMT2A | |
| SCHEMBL23235417 | 0.71 | CYP2C9 (0.46) | TDP1HTTMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4971979-A | Antiinflammatory agents | RHONE-POULENC SANTE (FR) | 1990-11-20 | — | — | US | disclosed |
| US-4886835-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC SANTE (FR) | 1989-12-12 | — | — | US | disclosed |