Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16277300 | 1.00 | HCAR2 (0.35) | HCAR2KEAP1NFE2L2DGAT1ESR1 | |
| SCHEMBL43764 | 0.85 | HCAR2 (0.45) | HCAR2KEAP1NFE2L2DGAT1 | |
| SCHEMBL43004 | 0.85 | HCAR2 (0.45) | HCAR2KEAP1NFE2L2DGAT1 | |
| SCHEMBL375029 | 0.85 | HCAR2 (0.45) | HCAR2KEAP1NFE2L2DGAT1 | |
| SCHEMBL19008840 | 0.83 | HCAR2 (0.39) | HCAR2KEAP1NFE2L2DGAT1ESR1 | |
| SCHEMBL7871608 | 0.82 | TSHR (0.41) | HCAR2DGAT1 | |
| SCHEMBL11283926 | 0.80 | DGAT1 (0.37) | HCAR2KEAP1NFE2L2DGAT1ESR1 | |
| SCHEMBL8740156 | 0.77 | TSHR (0.35) | HCAR2KEAP1NFE2L2DGAT1ESR1 | |
| SCHEMBL8740152 | 0.77 | TSHR (0.35) | HCAR2KEAP1NFE2L2DGAT1ESR1 | |
| SCHEMBL3878185 | 0.76 | HCAR2 (0.38) | HCAR2KEAP1NFE2L2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004047-B1 | COMPOUNDS OF '3-(5-SUBSTITUTED OXY-2,4-DINITRO-PHENYL)-2-OXO-PROPIONIC ACID ESTER', PROCESS AND APPLICATIONS THEREOF | ANTHEM BIOSCIENCES PVT LTD (IN) | 2017-02-22 | — | — | EP | claimed |
| EP-3004047-A1 | COMPOUNDS OF '3-(5-SUSTITUTED OXY-2,4-DINITRO-PHENYL)-2-OXO-PROPIONIC ACID ESTER', PROCESS AND APPLICATIONS THEREOF | Anthem Biosciences Pvt Ltd (IN) | 2016-04-13 | — | — | EP | claimed |
| WO-2014195896-A1 | COMPOUNDS OF '3-(5-SUSTITUTED OXY-2,4-DINITRO-PHENYL)-2-OXO-PROPIONIC ACID ESTER', PROCESS AND APPLICATIONS THEREOF | ANTHEM BIOSCIENCES PVT. LTD. (IN) | 2014-12-11 | — | — | WO | claimed |
| US-20140364613-A1 | COMPOUNDS OF 3-(5-SUSTITUTED OXY-2, 4-DINITROPHENYL)-2-OXO-PROPIONIC ACID ESTER, SYNTHESIS AND APPLICATIONS THEREOF | ANTHEM BIOSCIENCES PVT.LTD (IN) | 2014-12-11 | — | — | US | claimed |
| EP-3004047-B1 | COMPOUNDS OF '3-(5-SUBSTITUTED OXY-2,4-DINITRO-PHENYL)-2-OXO-PROPIONIC ACID ESTER', PROCESS AND APPLICATIONS THEREOF | ANTHEM BIOSCIENCES PVT LTD (IN) | 2017-02-22 | — | — | EP | disclosed |
| EP-3004047-A1 | COMPOUNDS OF '3-(5-SUSTITUTED OXY-2,4-DINITRO-PHENYL)-2-OXO-PROPIONIC ACID ESTER', PROCESS AND APPLICATIONS THEREOF | Anthem Biosciences Pvt Ltd (IN) | 2016-04-13 | — | — | EP | disclosed |
| US-9115128-B2 | Compounds of 3-(5-substituted Oxy-2, 4-dinitrophenyl)-2-oxo-propionic acid ester, synthesis and applications thereof | ANTHEM BIOSCIENCES PVT. LTD. (IN) | 2015-08-25 | — | — | US | disclosed |
| US-20140364613-A1 | COMPOUNDS OF 3-(5-SUSTITUTED OXY-2, 4-DINITROPHENYL)-2-OXO-PROPIONIC ACID ESTER, SYNTHESIS AND APPLICATIONS THEREOF | ANTHEM BIOSCIENCES PVT.LTD (IN) | 2014-12-11 | — | — | US | disclosed |
| WO-2014195896-A1 | COMPOUNDS OF '3-(5-SUSTITUTED OXY-2,4-DINITRO-PHENYL)-2-OXO-PROPIONIC ACID ESTER', PROCESS AND APPLICATIONS THEREOF | ANTHEM BIOSCIENCES PVT. LTD. (IN) | 2014-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364613-A1 | COMPOUNDS OF 3-(5-SUSTITUTED OXY-2, 4-DINITROPHENYL)-2-OXO-PROPIONIC ACID ESTER, SYNTHESIS AND APPLICATIONS THEREOF | SDHA, SDHB, SQOR | HCAR2 2007/4885KEAP1 437/4885NFE2L2 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.