Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.91 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.91 |
| ▸ | TSHR | P16473 | 1/20 | 0.91 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 7/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425872 | 0.96 | ALOX5 (1.00) | ALOX5CYP3A4TSHRKDM4EALDH1A1 | |
| SCHEMBL588131 | 0.96 | ALOX5 (1.00) | ALOX5CYP3A4TSHRKDM4EALDH1A1 | |
| SCHEMBL5720411 | 0.92 | ALOX5 (0.84) | ALOX5CYP3A4TSHRKDM4EALDH1A1 | |
| SCHEMBL11429113 | 0.89 | ALOX5 (0.88) | ALOX5CYP3A4TSHRKDM4EALDH1A1 | |
| Acrylic Acid SCHEMBL28239979 | 0.84 | ALOX5 (0.78) | ALOX5CYP3A4TSHRKDM4EALDH1A1 | |
| SCHEMBL10906841 | 0.84 | TSHR (0.78) | ALOX5CYP3A4TSHRKDM4EALDH1A1 | |
| SCHEMBL11418031 | 0.84 | ALOX5 (0.78) | ALOX5CYP3A4TSHRKDM4EALDH1A1 | |
| SCHEMBL11686576 | 0.81 | GAA (0.74) | ALOX5CYP3A4TSHRKDM4EALDH1A1 | |
| SCHEMBL8861401 | 0.78 | TSHR (0.63) | ALOX5CYP3A4TSHRKDM4EALDH1A1 | |
| SCHEMBL10942888 | 0.77 | CYP3A4 (0.68) | ALOX5CYP3A4TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912183-A | Free radical catalyst; calixarene derivative | LOCTITE (IRELAND) LTD. (IE) | 1990-03-27 | — | — | US | disclosed |