Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.48 |
| ▸ | PPARG | P37231 | 9/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696328 | 1.00 | PPARA (0.48) | PPARAPPARGNPC1CTRCPOLB | |
| SCHEMBL9695308 | 0.89 | PPARA (0.48) | PPARAPPARGCTRCPOLB | |
| SCHEMBL9695301 | 0.88 | PPARA (0.45) | PPARAPPARGCTRCPOLB | |
| SCHEMBL10420795 | 0.84 | PPARA (0.51) | PPARAPPARG | |
| SCHEMBL10419468 | 0.83 | PPARG (0.67) | PPARAPPARGCTRC | |
| SCHEMBL10420385 | 0.81 | PPARA (0.60) | PPARAPPARGCTRC | |
| SCHEMBL10420063 | 0.78 | PPARG (0.53) | PPARAPPARG | |
| SCHEMBL10419530 | 0.78 | PPARG (0.53) | PPARAPPARG | |
| SCHEMBL10419347 | 0.78 | PPARG (0.67) | PPARAPPARGNPC1CTRC | |
| SCHEMBL9614177 | 0.78 | PPARG (0.61) | PPARAPPARGCTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933367-A | Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1990-06-12 | — | — | US | disclosed |
| EP-0226636-B1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1989-02-08 | — | — | EP | disclosed |