Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.45 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696328 | 0.88 | PPARA (0.48) | PPARAPPARGCTRCPOLB | |
| SCHEMBL10420114 | 0.88 | PPARA (0.48) | PPARAPPARGCTRCPOLB | |
| SCHEMBL9695308 | 0.86 | PPARA (0.48) | PPARAPPARGCTRCPOLB | |
| SCHEMBL9696349 | 0.85 | PPARG (0.45) | PPARAPPARGNPSR1CTRCMEN1 | |
| SCHEMBL9696796 | 0.84 | PPARG (0.63) | PPARAPPARGCTRCPOLB | |
| SCHEMBL9614239 | 0.84 | PPARG (0.63) | PPARAPPARGCTRCPOLB | |
| SCHEMBL9614213 | 0.82 | PPARA (0.56) | PPARAPPARGMAPTCTRCALDH1A1 | |
| SCHEMBL9696319 | 0.81 | PPARG (0.61) | PPARAPPARGCTRC | |
| SCHEMBL9613840 | 0.78 | PPARG (0.59) | PPARAPPARGCTRCKDM4EALDH1A1 | |
| SCHEMBL9696474 | 0.77 | PPARG (0.56) | PPARAPPARGCTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507238-A1 | Optically active carboxylic acids and medicinal preparations containing them | Roche Diagnostics GmbH (DE) | 1992-10-07 | — | — | EP | claimed |
| EP-0507238-A1 | Optically active carboxylic acids and medicinal preparations containing them | Roche Diagnostics GmbH (DE) | 1992-10-07 | — | — | EP | disclosed |