Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26045956 | 0.82 | USP2 (0.35) | USP2LMNAMAPK1ARKDM4E | |
| SCHEMBL24652762 | 0.81 | HTT (0.36) | MAPK1KMT2ATSHR | |
| SCHEMBL22216870 | 0.81 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL2467812 | 0.80 | USP2 (0.39) | USP2LMNAMAPK1ARALDH1A1 | |
| SCHEMBL19636624 | 0.80 | USP2 (0.35) | USP2LMNAMAPK1ARALDH1A1 | |
| SCHEMBL11792489 | 0.78 | USP2 (0.38) | USP2LMNAMAPK1ARALDH1A1 | |
| SCHEMBL11423878 | 0.78 | USP2 (0.34) | USP2LMNAMAPK1ARALDH1A1 | |
| SCHEMBL6353254 | 0.77 | MAPK1 (0.41) | USP2LMNAMAPK1ARALDH1A1 | |
| SCHEMBL6269634 | 0.77 | LMNA (0.40) | USP2LMNAMAPK1ARALDH1A1 | |
| SCHEMBL116799 | 0.77 | MAPK1 (0.56) | USP2LMNAMAPK1ARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948588-A | ETHER DERIVATIVES OF GLYCEROLS OR POLYGLYCEROLS | KAO CORPORATION (JP) | 1990-08-14 | — | — | US | disclosed |
| US-4859696-A | Precutaneous absorption accelerator and preparation containing same | KAO CORPORATION (JP) | 1989-08-22 | — | — | US | disclosed |