Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | HPGD | P15428 | 3/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GGT1 | P19440 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315833 | 0.89 | KDM4E (1.00) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL29760302 | 0.89 | KDM4E (1.00) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL10420497 | 0.85 | KDM4E (0.84) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| Aspirin SCHEMBL10422109 | 0.79 | KDM4E (0.75) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL8667165 | 0.79 | KDM4E (0.79) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL4397553 | 0.76 | KDM4E (0.75) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| Piperidine SCHEMBL28209961 | 0.76 | KDM4E (0.73) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL2059537 | 0.75 | KDM4E (0.71) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL3382629 | 0.74 | KDM4E (0.72) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL5925554 | 0.74 | KDM4E (0.72) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918047-A | CONTAINING OXYSALICYLIC ACID DERIVATIVE AND ZINC COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0253666-A2 | Heat-sensitive recording material containing dye-forming components | FUJI PHOTO FILM CO., LTD. (JP) | 1988-01-20 | — | — | EP | disclosed |