Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.75 |
| ▸ | HPGD | P15428 | 4/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MYC | P01106 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GGT1 | P19440 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29760302 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL1315833 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL28317244 | 0.80 | ALDH1A1 (0.71) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL8415463 | 0.80 | KDM4E (0.71) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL30675634 | 0.80 | ALDH1A1 (0.70) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL305252 | 0.80 | ALDH1A1 (0.70) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL4399839 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL10420497 | 0.79 | KDM4E (0.84) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| Bicarbonate SCHEMBL4612198 | 0.78 | ALDH1A1 (0.68) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL9183165 | 0.78 | ALDH1A1 (0.68) | KDM4EALDH1A1HSD17B10HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572907-B2 | Methods and compounds for polynucleotide synthesis | AGILENT TECHNOLOGIES, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| EP-1717242-A1 | Polynucleotide synthesis | Agilent Technologies, Inc. (US) | 2006-11-02 | — | — | EP | disclosed |
| US-20060247430-A1 | Methods and compounds for polynucleotide synthesis | AGILENT TECHNOLOGIES, INC. | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247430-A1 | Methods and compounds for polynucleotide synthesis | POLN, POLRMT, POLM | KDM4E 4662/4885ALDH1A1 3888/4885HSD17B10 2662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.