Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556787 | 0.88 | ADRB2 (0.46) | ADRB2C3AR1TSHRMAPK1HIF1A | |
| SCHEMBL12287009 | 0.88 | ADRB2 (0.46) | ADRB2C3AR1TSHRMAPK1HIF1A | |
| SCHEMBL12288154 | 0.88 | ADRB2 (0.46) | ADRB2C3AR1TSHRMAPK1HIF1A | |
| SCHEMBL30798706 | 0.82 | ADRB2 (0.45) | ADRB2C3AR1TSHRMAPK1HIF1A | |
| SCHEMBL6682986 | 0.82 | SLC6A2 (0.45) | ADRB2C3AR1TSHRMAPK1HIF1A | |
| SCHEMBL6686877 | 0.80 | SLC6A2 (0.47) | ADRB2C3AR1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL1044614 | 0.80 | ADRB2 (0.43) | ADRB2C3AR1TSHRMAPK1HIF1A | |
| SCHEMBL1044613 | 0.80 | ADRB2 (0.43) | ADRB2C3AR1TSHRMAPK1HIF1A | |
| SCHEMBL12908530 | 0.80 | ADRB2 (0.43) | ADRB2C3AR1TSHRMAPK1HIF1A | |
| SCHEMBL11566936 | 0.80 | ADRB2 (0.48) | ADRB2C3AR1TSHRSLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933367-A | Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1990-06-12 | — | — | US | disclosed |
| EP-0226636-B1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1989-02-08 | — | — | EP | disclosed |