Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10421139 | 0.91 | REN (0.52) | REN | |
| SCHEMBL10422425 | 0.87 | REN (0.45) | RENCTSS | |
| SCHEMBL10420919 | 0.86 | REN (0.44) | RENCTSLCTSEP2RX1 | |
| SCHEMBL10709304 | 0.86 | REN (0.44) | RENCTSLCTSEP2RX1 | |
| SCHEMBL10422706 | 0.86 | REN (0.48) | REN | |
| SCHEMBL10421590 | 0.86 | REN (0.44) | RENCTSLCTSEP2RX1 | |
| SCHEMBL10420914 | 0.84 | REN (0.46) | REN | |
| SCHEMBL10709088 | 0.84 | REN (0.46) | REN | |
| SCHEMBL10421231 | 0.84 | REN (0.46) | REN | |
| SCHEMBL10421337 | 0.84 | REN (0.49) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904660-A | HYPOTENSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |