Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 11/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 11/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 11/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.49 |
| ▸ | PLG | P00747 | 17/20 | 0.47 |
| ▸ | PLAU | P00749 | 3/20 | 0.47 |
| ▸ | F11 | P03951 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365350 | 1.00 | PRSS1 (0.49) | PRSS1PRSS2PRSS3KLKB1PLG | |
| Hydrochloric Acid SCHEMBL10419782 | 0.99 | PRSS1 (0.49) | PRSS1PRSS2PRSS3KLKB1PLG | |
| Hydrochloric Acid SCHEMBL10419784 | 0.99 | PRSS1 (0.49) | PRSS1PRSS2PRSS3KLKB1PLG | |
| Hydrochloric Acid SCHEMBL7430320 | 0.92 | PRSS1 (0.48) | PRSS1PRSS2PRSS3KLKB1PLG | |
| Hydrochloric Acid SCHEMBL7430308 | 0.92 | PRSS1 (0.48) | PRSS1PRSS2PRSS3KLKB1PLG | |
| SCHEMBL7403085 | 0.87 | ATM (0.43) | PRSS1PRSS2PRSS3PLGPLAU | |
| SCHEMBL7403089 | 0.87 | ATM (0.43) | PRSS1PRSS2PRSS3PLGPLAU | |
| SCHEMBL7434196 | 0.81 | PRSS1 (0.49) | PRSS1PRSS2PRSS3KLKB1PLG | |
| Hydrochloric Acid SCHEMBL7365367 | 0.80 | BCL2 (0.49) | — | |
| Dalfampridine SCHEMBL10421059 | 0.77 | KMT2A (0.48) | PRSS1PRSS2PRSS3PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4895842-A | Phenylalanine derivative and proteinase inhibitor | SHOSUKE OKAMOTO (JP) | 1990-01-23 | — | — | US | disclosed |