Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 5/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.39 |
| ▸ | PLG | P00747 | 6/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403089 | 1.00 | ATM (0.43) | ATMKMT2AMEN1BCL2MCL1 | |
| Dalfampridine SCHEMBL10421059 | 0.89 | KMT2A (0.48) | ATMKMT2AMEN1BCL2MCL1 | |
| SCHEMBL7365350 | 0.87 | PRSS1 (0.49) | PLGPRSS1PRSS2PRSS3PLAU | |
| SCHEMBL10420943 | 0.87 | PRSS1 (0.49) | PLGPRSS1PRSS2PRSS3PLAU | |
| Hydrochloric Acid SCHEMBL10419784 | 0.87 | PRSS1 (0.49) | PLGPRSS1PRSS2PRSS3PLAU | |
| Hydrochloric Acid SCHEMBL10419782 | 0.87 | PRSS1 (0.49) | PLGPRSS1PRSS2PRSS3PLAU | |
| Hydrochloric Acid SCHEMBL7365367 | 0.86 | BCL2 (0.49) | BCL2MCL1 | |
| Hydrochloric Acid SCHEMBL7430308 | 0.80 | PRSS1 (0.48) | PLGPRSS1PRSS2PRSS3PLAU | |
| Hydrochloric Acid SCHEMBL7430320 | 0.80 | PRSS1 (0.48) | PLGPRSS1PRSS2PRSS3PLAU | |
| SCHEMBL16604396 | 0.73 | F11 (0.61) | ATMKMT2AMEN1PLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217286-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1987-04-08 | — | — | EP | disclosed |