SCHEMBL10421235

SCHEMBL10421235

CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC1CCCCC1)C(O)CSc1nnnn1CC(N)=O

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.50
▸ PGC P20142 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10707387 1.00 REN (0.50) RENPGC
SCHEMBL10421174 0.92 REN (0.55) RENPGC
SCHEMBL10422718 0.92 REN (0.55) RENPGC
SCHEMBL10707389 0.84 REN (0.41) RENPGC
SCHEMBL10421236 0.84 REN (0.41) RENPGC
SCHEMBL7382612 0.83 REN (0.58) RENPGC
SCHEMBL10540148 0.82 REN (0.60) RENPGC
SCHEMBL10422714 0.81 REN (0.51) RENPGC
SCHEMBL7271925 0.81 REN (0.57) RENPGC
SCHEMBL7386767 0.81 REN (0.57) RENPGC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4904660-A HYPOTENSIVE AGENTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1990-02-27 — — US disclosed
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