SCHEMBL10421241

SCHEMBL10421241

CC(C)(C)OC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC1CCCCC1)C(O)CSc1nccs1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.57
▸ PGC P20142 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10421240 0.87 REN (0.46) RENPGC
SCHEMBL7275988 0.82 REN (0.68) RENPGC
SCHEMBL27692369 0.75 REN (0.73) RENPGC
SCHEMBL27692370 0.75 REN (0.73) RENPGC
SCHEMBL27692368 0.73 REN (0.80) RENPGC
SCHEMBL27673813 0.73 REN (0.79) RENPGC
SCHEMBL27692375 0.72 REN (0.69) RENPGC
SCHEMBL27692472 0.72 REN (0.68) RENPGC
SCHEMBL10710118 0.71 REN (0.49) REN
SCHEMBL10422413 0.71 REN (0.51) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4904660-A HYPOTENSIVE AGENTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1990-02-27 — — US disclosed
Send feedback