Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512465 | 0.96 | MAPT (0.69) | MAPTHSD17B10ELANELMNAGAA | |
| SCHEMBL9493542 | 0.89 | MAPT (0.78) | MAPTHSD17B10TDP1LMNASLC1A5 | |
| SCHEMBL9493539 | 0.89 | MAPT (0.78) | MAPTHSD17B10TDP1LMNASLC1A5 | |
| SCHEMBL8956806 | 0.89 | MAPT (0.78) | MAPTHSD17B10TDP1LMNASLC1A5 | |
| SCHEMBL10423302 | 0.88 | HSD17B10 (0.50) | MAPTHSD17B10ELANETDP1LMNA | |
| SCHEMBL10423314 | 0.87 | MAPT (0.62) | MAPTHSD17B10ELANELMNAGAA | |
| SCHEMBL9511839 | 0.86 | MAPT (0.61) | MAPTTDP1LMNASLC1A5ADRB2 | |
| SCHEMBL10908261 | 0.86 | MAPT (0.61) | MAPTLMNASLC1A5ADRB2ADRB1 | |
| SCHEMBL10613424 | 0.86 | MAPT (0.61) | MAPTSLC1A5ADRB2ADRB1ADRB3 | |
| SCHEMBL10610558 | 0.86 | MAPT (0.61) | MAPTLMNASLC1A5ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174816-B1 | BIPHENYL-BASED DIESTER COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SAME | AJINOMOTO CO., INC. (JP) | 1990-05-23 | — | — | EP | disclosed |
| US-4831182-A | Biphenyl-based diester compounds and liquid crystal compositions containing same | AJINOMOTO CO., INC. (JP) | 1989-05-16 | — | — | US | disclosed |
| US-4695651-A | Biphenyl-based diester compounds and liquid crystal compositions containing same | AJINOMOTO CO., INC. (JP) | 1987-09-22 | — | — | US | disclosed |
| EP-0174816-A2 | Biphenyl-based diester compounds and liquid crystal compositions containing same | AJINOMOTO CO., INC. (JP) | 1986-03-19 | — | — | EP | disclosed |