Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | ELANE | P08246 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10422606 | 0.96 | MAPT (0.64) | MAPTELANEHSD17B10KMT2AADRB2 | |
| SCHEMBL5368475 | 0.88 | MAPT (0.86) | MAPTHSD17B10ADRB2ADRB1ADRB3 | |
| SCHEMBL9579629 | 0.87 | ELANE (0.54) | MAPTELANEHSD17B10KMT2AADRB2 | |
| SCHEMBL9628197 | 0.87 | MAPT (0.52) | MAPTELANEHSD17B10KMT2AADRB2 | |
| SCHEMBL9628186 | 0.87 | MAPT (0.52) | MAPTELANEHSD17B10KMT2AADRB2 | |
| SCHEMBL7133911 | 0.86 | MAPT (0.68) | MAPTELANEKMT2AADRB2ADRB1 | |
| SCHEMBL7133920 | 0.86 | MAPT (0.68) | MAPTELANEKMT2AADRB2ADRB1 | |
| SCHEMBL1988771 | 0.86 | MAPT (0.71) | MAPTHSD17B10KMT2AADRB2ADRB1 | |
| SCHEMBL9456360 | 0.85 | MAPT (0.66) | MAPTKMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL4953172 | 0.85 | MAPT (0.66) | MAPTKMT2AADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344779-B1 | Liquid-crystalline organopolysiloxanes | TORAY SILICONE CO (JP) | 1993-10-20 | — | — | EP | disclosed |
| EP-0344779-A2 | Liquid-crystalline organopolysiloxanes | TORAY SILICONE COMPANY, LIMITED (JP) | 1989-12-06 | — | — | EP | disclosed |