SCHEMBL1042267

SCHEMBL1042267

C=CCOc1cccc2ccc3cc4ccccc4cc3c12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.48
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA9 Q16790 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2A6 P11509 1/20 0.40
MAPT P10636 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
LIG1 P18858 1/20 0.39
TXNRD1 Q16881 1/20 0.39
TXNRD3 Q86VQ6 1/20 0.39
TXNRD2 Q9NNW7 1/20 0.39
SETDB1 Q15047 1/20 0.39
ERBB2 P04626 1/20 0.38
CYP1A2 P05177 1/20 0.38
FYN P06241 1/20 0.38
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27876309 0.85 HPGD (0.45) HPGDTSHRMAPK1HSD17B10CA12
SCHEMBL3822715 0.82 HPGD (0.51) HPGDTSHRMAPK1HSD17B10CA12
SCHEMBL5413465 0.80 HPGD (0.49) HPGDTSHRMAPK1HSD17B10CA12
SCHEMBL21433765 0.77 HTR1B (0.43) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL1073250 0.77 CYP1A2 (0.47) HPGDTSHRMAPK1HSD17B10CYP3A4
SCHEMBL4563111 0.77 HPGD (0.46) HPGDTSHRMAPK1HSD17B10CA12
SCHEMBL3822490 0.76 HPGD (0.49) HPGDTSHRMAPK1HSD17B10CA12
SCHEMBL4371294 0.75 HPGD (0.56) HPGDTSHRMAPK1HSD17B10CA12
SCHEMBL7119674 0.75 HPGD (0.49) HPGDTSHRMAPK1HSD17B10CA12
SCHEMBL3824435 0.75 MTNR1A (0.51) HPGDTSHRMAPK1HSD17B10CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4253796-A None JP disclosed
CN-118139953-A Grease composition and grease-sealed bearing NTN株式会社 2024-06-04 CN disclosed
CN-116761946-A Deep groove ball bearing 日本精工株式会社 2023-09-15 CN disclosed
CN-111139117-B Lubricant composition containing an anti-flaking agent 协同油脂株式会社 2023-03-24 CN disclosed
WO-2022045233-A1 GREASE COMPOSITION, AND ROLLING BEARING NTN株式会社 2022-03-03 WO disclosed
EP-3666860-A1 ANTI-FLAKING AGENT AND LUBRICANT COMPOSITION COMPRISING THE SAME Kyodo Yushi Co., Ltd. (JP) 2020-06-17 EP disclosed
CN-111139117-A Anti-flaking agent and lubricant composition containing same 协同油脂株式会社 2020-05-12 CN disclosed
WO-2020054802-A1 GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT 出光興産株式会社 2020-03-19 WO disclosed
EP-2518132-B1 Rust resisting grease composition, grease-enclosed bearing, and rust resisting agent for use in grease composition NTN TOYO BEARING CO LTD (JP) 2018-06-06 EP disclosed
EP-2275699-B1 GREASE-PACKED DEEP GROOVE BALL BEARING FOR OUTER-RING ROTATION NTN TOYO BEARING CO LTD (JP) 2016-05-11 EP disclosed
US-20060101935-A1 Linear motion device NSK LTD. 2006-05-18 US disclosed
US-20050261141-A1 Rolling bearing, rolling bearing for fuel cell, compressor for fuel cell system and fuel cell system NSK LTD. 2005-11-24 US disclosed
US-6919301-B2 Grease composition and rolling apparatus NSK LTD. (JP) 2005-07-19 US disclosed
US-20030176298-A1 Grease composition and rolling apparatus NSK LTD. (JP) 2003-09-18 US disclosed
CN-1070910-C Lubricating grease composition HITACHI LTD (JP) 2001-09-12 CN disclosed
US-5922654-A TWO OR MORE ORGANOMETALLIC COMPOUNDS WHERE THE METAL IS A TRANSITION METAL OR SEMIMETAL, OR ZINC; FOR EXAMPLE, ZINC DIALKYLDITHIOPHOSPHATE, OR NICKEL DIALKYLDITHIOCARBAMATE; HIGHER LOAD BEARING PROPERTIES, HIGH TEMPERATURE PERFORMANCE NSK LTD. (JP) 1999-07-13 US disclosed
CN-1203260-A Lubricating grease composition HITACHI LTD (JP) 1998-12-30 CN disclosed
CN-1040124-C Lubricating oil composition HITACHI LTD (JP) 1998-10-07 CN disclosed
CN-1136074-A Lubricating oil composition and grease composition HITACHI LTD (JP) 1996-11-20 CN disclosed
JP-H04253796-A HIGH-TEMPERATURE-DURABLE GREASE COMPOSITION NTN CORP 1992-09-09 JP disclosed