Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 8/20 | 0.34 |
| ▸ | MAOA | P21397 | 8/20 | 0.34 |
| ▸ | MAOB | P27338 | 8/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25520742 | 0.82 | SMYD2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2KDM1A | |
| SCHEMBL25520744 | 0.82 | SMYD2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2KDM1A | |
| SCHEMBL23670835 | 0.81 | SMYD2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2ABL1 | |
| SCHEMBL2914349 | 0.79 | RIPK1 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL22397155 | 0.78 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2ABL1 | |
| SCHEMBL10517030 | 0.77 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2KDM1A | |
| SCHEMBL10518519 | 0.77 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2KDM1A | |
| SCHEMBL10380887 | 0.77 | SMYD2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL10236926 | 0.77 | SMYD2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL19285623 | 0.77 | SMYD2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366059-A2 | Carbocyclic nucleoside analogs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-05-02 | — | — | EP | disclosed |