Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10422805 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2HPGDF2DGAT1KDM4E | |
| SCHEMBL10422803 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2HPGDF2DGAT1KDM4E | |
| SCHEMBL8742524 | 0.86 | F2 (0.39) | SMN1; SMN2HPGDF2KDM4EALDH1A1 | |
| SCHEMBL7524914 | 0.86 | F2 (0.39) | SMN1; SMN2HPGDF2KDM4EALDH1A1 | |
| SCHEMBL7524908 | 0.86 | F2 (0.39) | SMN1; SMN2HPGDF2KDM4EALDH1A1 | |
| SCHEMBL8742532 | 0.86 | F2 (0.39) | SMN1; SMN2HPGDF2KDM4EALDH1A1 | |
| SCHEMBL9154528 | 0.83 | RAB9A (0.51) | SMN1; SMN2HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL9154524 | 0.83 | RAB9A (0.51) | SMN1; SMN2HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8742558 | 0.83 | RAB9A (0.51) | SMN1; SMN2HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7524392 | 0.83 | XIAP (0.39) | SMN1; SMN2HPGDF2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4952699-A | Liquid-crystalline, 2,5-disubstituted, 1,3,4-thiadiazoles with extended smectic C phases | VEB WERK FUER FERNSEHELEKTRONIK IM VEB KOMBINAT MIKROELEKTRONIK (DD) | 1990-08-28 | — | — | US | disclosed |