Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 2/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10423647 | 0.93 | MEN1 (0.38) | TYMPMEN1KMT2AKIF11 | |
| SCHEMBL10423655 | 0.93 | MEN1 (0.38) | TYMPMEN1KMT2AKIF11 | |
| SCHEMBL10423644 | 0.89 | TYMP (0.38) | TYMPSLC6A11SLC6A1MEN1KMT2A | |
| SCHEMBL10423643 | 0.89 | TYMP (0.38) | TYMPSLC6A11SLC6A1MEN1KMT2A | |
| SCHEMBL14387754 | 0.87 | TYMP (0.41) | TYMPSLC6A11SLC6A1MEN1KMT2A | |
| SCHEMBL9694704 | 0.87 | TYMP (0.44) | TYMPSLC6A11SLC6A1MEN1KMT2A | |
| SCHEMBL10423328 | 0.87 | TYMP (0.44) | TYMPSLC6A11SLC6A1MEN1KMT2A | |
| SCHEMBL14029917 | 0.87 | TYMP (0.41) | TYMPSLC6A11SLC6A1MEN1KMT2A | |
| SCHEMBL9208332 | 0.87 | TYMP (0.44) | TYMPSLC6A11SLC6A1MEN1KMT2A | |
| SCHEMBL9212681 | 0.87 | TYMP (0.44) | TYMPSLC6A11SLC6A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898936-A | ANTITUMOR AGENTS | PCR, INC. (US) | 1990-02-06 | — | — | US | disclosed |