Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10423644 | 1.00 | TYMP (0.38) | TYMPKCNA5SLC6A1SLC6A11PDE4D | |
| SCHEMBL10423648 | 0.94 | PDE4D (0.38) | TYMPPDE4DPSEN1PSEN2APH1B | |
| SCHEMBL10423649 | 0.94 | PDE4D (0.38) | TYMPPDE4DPSEN1PSEN2APH1B | |
| SCHEMBL10423331 | 0.89 | TYMP (0.41) | TYMPSLC6A1SLC6A11CYP3A4CYP2C19 | |
| SCHEMBL10758604 | 0.85 | PDE4D (0.38) | TYMPPDE4DPSEN1PSEN2APH1B | |
| SCHEMBL10758609 | 0.85 | PDE4D (0.38) | TYMPPDE4DPSEN1PSEN2APH1B | |
| SCHEMBL10423655 | 0.82 | MEN1 (0.38) | TYMPMEN1KMT2AKIF11 | |
| SCHEMBL10423647 | 0.82 | MEN1 (0.38) | TYMPMEN1KMT2AKIF11 | |
| SCHEMBL9212681 | 0.81 | TYMP (0.44) | TYMPSLC6A1SLC6A11CYP3A4MEN1 | |
| SCHEMBL9208332 | 0.81 | TYMP (0.44) | TYMPSLC6A1SLC6A11CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898936-A | ANTITUMOR AGENTS | PCR, INC. (US) | 1990-02-06 | — | — | US | claimed |
| US-4898936-A | ANTITUMOR AGENTS | PCR, INC. (US) | 1990-02-06 | — | — | US | disclosed |