Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 9/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 9/20 | 0.64 |
| ▸ | RELA | Q04206 | 9/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14586681 | 0.78 | NFKB1 (1.00) | NFKB1NFKB2RELAGAABTK | |
| SCHEMBL14586683 | 0.78 | NFKB1 (1.00) | NFKB1NFKB2RELAGAABTK | |
| SCHEMBL5600252 | 0.78 | NFKB1 (1.00) | NFKB1NFKB2RELAGAABTK | |
| SCHEMBL25567964 | 0.75 | NFKB1 (0.75) | NFKB1NFKB2RELAGAABTK | |
| SCHEMBL6917362 | 0.75 | NFKB1 (0.75) | NFKB1NFKB2RELAGAABTK | |
| SCHEMBL22227389 | 0.75 | NFKB1 (0.75) | NFKB1NFKB2RELAGAABTK | |
| SCHEMBL9622035 | 0.73 | NFKB1 (0.49) | NFKB1NFKB2RELAGAAEPHX2 | |
| SCHEMBL9621924 | 0.72 | NFKB1 (0.48) | NFKB1NFKB2RELAGAAEPHX2 | |
| SCHEMBL9622577 | 0.72 | NFKB1 (0.48) | NFKB1NFKB2RELAGAAEPHX2 | |
| SCHEMBL15502088 | 0.71 | GAA (0.54) | NFKB1NFKB2RELAGAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959493-A | CENTRAL NERVOUS SYSTEM DISORDERS | SUNTORY LIMITED (JP) | 1990-09-25 | — | — | US | disclosed |